KIT anticorps (AA 100-300)

N° du produit ABIN6294267

Cet anticorps anti-KIT Monoclonal Souris (ABIN6294267) détecte spécifiquement KIT dans WB, FACS, IF et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour KIT anticorps (AA 100-300) (ABIN6294267)

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KIT est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-KIT anticorps

Épitope: AA 100-300

Fonction: Mouse anti-Human c-Kit Antibody [Sodium Azide Free]

Specificité: Cell surface and cytoplasmic

Purification: A recombinant human fragment around amino acids 100-300 was used as the immunogen for the c-Kit antibody.

Immunogène: A recombinant human fragment around amino acids 100-300 was used as the immunogen for the c-Kit antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: (0.5-1 μg/mL for 2 hours at RT)
Immunohistochemistry (Frozen Only): 2-4 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur KIT

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Autre désignation: Mast/stem cell growth factor receptor Kit

Sujet:

Target Description: This mAb recognizes a protein of 145 kDa, identified as CD117/p145kit/c-Kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117/c-Kit has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117/c-Kit is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

Gene Symbol: KIT///SCFR

ID gène: 3815

UniProt: P10721

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity