PODXL anticorps (Extracellular Domain)
Aperçu rapide pour PODXL anticorps (Extracellular Domain) (ABIN6295450)
Antigène
Voir toutes PODXL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Extracellular Domain
-
Fonction
- Mouse anti-Human/Rabbit/Rat Podocalyxin Antibody [Sodium Azide Free]
-
Specificité
- Cell surface and cytoplasmic
-
Purification
- A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.
-
Immunogène
- A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.
-
-
-
-
Indications d'application
-
FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IP: 1-2 μg/500 μg protein
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Restrictions
- For Research Use only
-
-
-
Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- PODXL (Podocalyxin-Like (PODXL))
-
Autre désignation
- Podocalyxin
-
Sujet
-
Target Description: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Gene Symbol: PODXL///PCLP///PCLP1
-
ID gène
- 5420
-
UniProt
- O00592
-
Pathways
- Tube Formation
Antigène
-