CLTA anticorps (N-Term)

N° du produit ABIN6295474

Cet anticorps Souris Monoclonal détecte spécifiquement CLTA dans WB, IHC, FACS et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour CLTA anticorps (N-Term) (ABIN6295474)

Antigène: CLTA (Clathrin, Light Chain A (CLTA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLTA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-CLTA anticorps

Épitope: N-Term

Fonction: Mouse anti-Human Clatherin Light Chain Antibody (LCA/LCB) [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.

Immunogène: A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CLTA

Antigène: CLTA (Clathrin, Light Chain A (CLTA))

Autre désignation: Clathrin light chain A

Sujet:

Target Description: Recognizes proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60 % homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Gene Symbol: CLTA///CLTB

UniProt: P09496, P09497

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation