IGF1 anticorps

N° du produit ABIN6296313

Cet anticorps anti-IGF1 est un anticorps Souris Monoclonal détectant IGF1 dans IF, FACS, Neut, AcA, in vitro et Func. Adapté pour Humain, Souris, Rat et Lapin.

Aperçu rapide pour IGF1 anticorps (ABIN6296313)

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reactivité: Humain, Souris, Rat, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF1 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Neutralization (Neut), Activity Assay (AcA), In vitro Assay (in vitro), Functional Studies (Func)

Détail du produit anti-IGF1 anticorps

Fonction: Mouse anti-Human/Mouse/Rat/Rabbit IGF-1 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic (secreted)

Purification: Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.

Immunogène: Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Functional Activity: In-vitro neutralization of biological activity of IGF-1 (Order SAF formulation)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur IGF1

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Autre désignation: Insulin-like growth factor I

Sujet:

Target Description: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Gene Symbol: IGF1///IBP1

ID gène: 3479

UniProt: P05019

Pathways: Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation