XRCC6 anticorps

N° du produit ABIN6296746

Cet anticorps Souris Monoclonal détecte spécifiquement XRCC6 dans IF, FACS et ICC. Il présente une réactivité avec des échantillons de Humain et Primate.

Aperçu rapide pour XRCC6 anticorps (ABIN6296746)

Antigène: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp XRCC6 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-XRCC6 anticorps

Fonction: Mouse anti-Human/Primates Ku70 + Ku80 Antibody [Sodium Azide Free]

Specificité: Nuclear

Purification: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Immunogène: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Information d'application

Indications d'application: Flow cytometry: 0.5-1 μg/10e6 cells
IF: 0.5-1.0 μg/mL
Immunocytochemistry (Acetone-fixed cells): 0.25-0.5 μg/mL for 30 minutes at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur XRCC6

Antigène: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Autre désignation: X-ray repair cross-complementing protein 6

Sujet:

Target Description: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Gene Symbol: XRCC6///G22P1

ID gène: 2547

UniProt: P12956

Pathways: Réparation de l'ADN