IGF1 anticorps

N° du produit ABIN6296855

L’anticorps Souris Monoclonal anti-IGF1 a été validé pour IF, FACS, AcA, in vitro, Func et Inhibition. Il convient pour détecter IGF1 dans des échantillons de Humain, Souris, Rat et Lapin.

Aperçu rapide pour IGF1 anticorps (ABIN6296855)

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reactivité: Humain, Souris, Rat, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF1 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Activity Assay (AcA), In vitro Assay (in vitro), Functional Studies (Func), Blocking Antibody (Inhibition)

Détail du produit anti-IGF1 anticorps

Fonction: Mouse anti-Human/Mouse/Rat/Rabbit IGF1 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic (Secreted)

Purification: Purified human IGF1 protein was used as the immunogen for this antibody.

Immunogène: Purified human IGF1 protein was used as the immunogen for this antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
Functional Activity: In vitro inhibition of IGF1 Activity, order BSA/azide free format

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur IGF1

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Autre désignation: Insulin-like growth factor I

Sujet:

Target Description: This antibody is specific to IGF1 (Insulin like Growth Factor 1) and shows minimal cross-reaction with IGF11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF1B while isoform 2 is known as IGF1A. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of the IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Gene Symbol: IGF1///IBP1

ID gène: 3479

UniProt: P05019

Pathways: Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation