JUP anticorps

N° du produit ABIN6296917

Cet anticorps Souris Monoclonal détecte spécifiquement JUP dans WB, IF et IP. Il présente une réactivité envers Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien et Cat.

Aperçu rapide pour JUP anticorps (ABIN6296917)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien, Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-JUP anticorps

Fonction: Mouse anti-Human/Mouse/Rat/Cat/Dog/Chicken/Cow Gamma Catenin Antibody / Plakoglobin [Sodium Azide Free]

Specificité: Cell surface, cytoplasmic, cell junctions

Purification: Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.

Immunogène: Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.

Information d'application

Indications d'application: Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunoprecipitation: suitable

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: Junction plakoglobin

Sujet:

Target Description: Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). [UniProt]

Gene Symbol: JUP///CTNNG///DP3

ID gène: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location