CD80 anticorps

N° du produit ABIN6297276

Cet anticorps anti-CD80 Monoclonal Souris (ABIN6297276) détecte spécifiquement CD80 dans FACS, ELISA, IF et Coat. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD80 anticorps (ABIN6297276)

Antigène: CD80

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Coating (Coat)

Détail du produit anti-CD80 anticorps

Fonction: Mouse anti-Human CD80 Antibody / B7-1 [Sodium Azide Free]

Specificité: Cytoplasmic, membranous

Purification: Recombinant human protein used as the immunogen for the CD80 antibody.

Immunogène: Recombinant human protein used as the immunogen for the CD80 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL,ELISA (protein): order BSA free formulation for coating

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD80

Antigène: CD80

Autre désignation: T-lymphocyte activation antigen CD80

Sujet:

Target Description: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

Gene Symbol: CD80///CD28LG///CD28LG1///LAB7

ID gène: 941

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints