ErbB2/Her2 anticorps

N° du produit ABIN6297525

Cet anticorps anti-ErbB2/Her2 Monoclonal Souris (ABIN6297525) détecte spécifiquement ErbB2/Her2 dans IF et FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour ErbB2/Her2 anticorps (ABIN6297525)

Antigène: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ErbB2/Her2 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-ErbB2/Her2 anticorps

Fonction: Mouse anti-Human/Rat ErbB2 Antibody HER2 [Sodium Azide Free]

Specificité: Extracellular/Intracellular cell membrane

Purification: Recombinant human protein was used as the immunogen for this ErbB2 antibody.(1)

Immunogène: Recombinant human protein was used as the immunogen for this ErbB2 antibody.(1)

Information d'application

Indications d'application: FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur ErbB2/Her2

Antigène: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Autre désignation: Receptor tyrosine-protein kinase erbB-2

Sujet:

Target Description: This antibody recognizes a protein of 185 kDa, which is identified as HER2 / ErbB2. Its epitope is localized in the extracellular domain. ErbB2 is a member of the EGFR family. This antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. ErbB2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

Gene Symbol: ERBB2///HER2///MLN19///NEU///NGL

ID gène: 2064

UniProt: P04626

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development