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CD25 anticorps

IL2RA Reactivité: Humain FACS, IF, Func Hôte: Souris Monoclonal unconjugated
N° du produit ABIN6297678
  • Antigène Voir toutes CD25 (IL2RA) Anticorps
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Reactivité
    • 187
    • 127
    • 38
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 149
    • 98
    • 80
    • 2
    • 1
    Souris
    Clonalité
    • 249
    • 77
    • 2
    Monoclonal
    Conjugué
    • 113
    • 34
    • 29
    • 27
    • 22
    • 11
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD25 est non-conjugé
    Application
    • 223
    • 91
    • 57
    • 50
    • 43
    • 41
    • 22
    • 18
    • 14
    • 14
    • 10
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    Fonction
    Mouse anti-Human CD25 Antibody [Sodium Azide Free]
    Specificité
    Cell surface
    Purification
    Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
    Immunogène
    Stimulated human leukocytes were used as the immunogen for the CD25 antibody.
    Top Product
    Discover our top product IL2RA Anticorps primaire
  • Indications d'application
    Functional Activity (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Agent conservateur
    Azide free
    Stock
    4 °C,-20 °C
    Stockage commentaire
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Antigène
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Autre désignation
    Interleukin-2 receptor subunit alpha (IL2RA Produits)
    Synonymes
    anticorps CD25, anticorps IDDM10, anticorps IL2R, anticorps TCGFR, anticorps IL2RAC, anticorps IL-2RA, anticorps Il2r, anticorps Ly-43, anticorps interleukin 2 receptor subunit alpha, anticorps interleukin-2 receptor subunit alpha-like, anticorps interleukin 2 receptor, alpha chain, anticorps IL2RA, anticorps Il2ra, anticorps LOC100222957
    Sujet

    Target Description: Recognizes a protein of 55 kDa, identified as CD25 (Workshop IV, Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 Molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R b-chain, p75) and CD132 (common g-chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This mAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.

    Gene Symbol: IL2RA

    ID gène
    3559
    UniProt
    P01589
    Pathways
    Signalistation JAK/STAT, Growth Factor Binding, Activated T Cell Proliferation
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