CD63 anticorps (PE)

N° du produit ABIN6297775

Cet anticorps Souris Monoclonal détecte spécifiquement CD63 dans FACS, IF et T. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CD63 anticorps (PE) (ABIN6297775)

Antigène: CD63

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD63 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Détail du produit anti-CD63 anticorps (PE)

Fonction: Mouse anti-Human/Mouse CD63 Antibody [PE Conjugated]

Specificité: Cytoplasmic

Purification: The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.

Immunogène: The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.

Information d'application

Indications d'application: Flow Cytometry: 5 µL/test/million cells or 5 µL/test/100 µL of whole blood
Immunofluorescence: 1:50-1:100 for 30 minutes at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C. The conjugate is light-sensitive, protect from light.

Détails sur CD63

Antigène: CD63

Autre désignation: CD63 antigen

Sujet:

Target Description: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Gene Symbol: CD63///MLA1///TSPAN30

ID gène: 967

UniProt: P08962