MUSK anticorps
Aperçu rapide pour MUSK anticorps (ABIN6297871)
Antigène
Voir toutes MUSK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit Anti-MUSK Antibody
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Immunogène
- This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
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Restrictions
- For Research Use only
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
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Autre désignation
- MUSK
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Sujet
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Target Description: MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Gene Symbol: MUSK
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ID gène
- 4593
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UniProt
- O15146
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Pathways
- Signalisation RTK, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
Antigène
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