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CAMLG anticorps (N-Term)

CAMLG Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN630925
  • Antigène Voir toutes CAMLG Anticorps
    CAMLG (Calcium Modulating Ligand (CAMLG))
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 39
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 36
    • 6
    • 1
    Lapin
    Clonalité
    • 40
    • 3
    Polyclonal
    Conjugué
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CAMLG est non-conjugé
    Application
    • 33
    • 19
    • 14
    • 6
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB)
    Specificité
    CAMLG antibody was raised against the N terminal of CAMLG
    Purification
    Affinity purified
    Immunogène
    CAMLG antibody was raised using the N terminal of CAMLG corresponding to a region with amino acids LLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRV
    Top Product
    Discover our top product CAMLG Anticorps primaire
  • Indications d'application
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    CAMLG Blocking Peptide, catalog no. 33R-5170, is also available for use as a blocking control in assays to test for specificity of this CAMLG antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CAMLG antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène
    CAMLG (Calcium Modulating Ligand (CAMLG))
    Autre désignation
    CAMLG (CAMLG Produits)
    Synonymes
    anticorps MGC53900, anticorps CAML, anticorps AI385748, anticorps Camlg, anticorps Caml, anticorps calcium modulating ligand L homeolog, anticorps calcium modulating ligand, anticorps camlg.L, anticorps CAMLG, anticorps camlg, anticorps Caml, anticorps Camlg
    Sujet
    The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
    Poids moléculaire
    33 kDa (MW of target protein)
    Pathways
    EGFR Signaling Pathway
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