POLI anticorps
Aperçu rapide pour POLI anticorps (ABIN633154)
Antigène
Voir toutes POLI AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purified
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Immunogène
- POLI antibody was raised using a synthetic peptide corresponding to a region with amino acids PVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSGHVYNNQSINLLD
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Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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POLI Blocking Peptide, (ABIN5615457), is also available for use as a blocking control in assays to test for specificity of this POLI antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of POLI antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- POLI (Polymerase (DNA Directed) iota (POLI))
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Autre désignation
- POLI
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Sujet
- POLI is an error-prone DNA polymerase specifically involved in DNA repair.POLI plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. POLI favors Hoogsteen base-pairing in the active site.POLI inserts the correct base with high-fidelity opposite an adenosine template.
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Poids moléculaire
- 83 kDa (MW of target protein)
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Pathways
- Réparation de l'ADN
Antigène
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