Prohibitin anticorps (C-Term)

N° du produit ABIN634116

Cet anticorps anti-Prohibitin est un anticorps Lapin Polyclonal détectant Prohibitin dans WB et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Prohibitin anticorps (C-Term) (ABIN634116)

Antigène: Prohibitin (PHB)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Prohibitin anticorps

Épitope: C-Term

Specificité: Prohibitin antibody was raised against the C terminal of PHB

Purification: Affinity purified

Immunogène: Prohibitin antibody was raised using the C terminal of PHB corresponding to a region with amino acids AEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLS

Information d'application

Indications d'application: WB: 1-2 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

Prohibitin Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this Prohibitin antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHB antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur Prohibitin

Antigène: Prohibitin (PHB)

Autre désignation: Prohibitin

Sujet: Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

Poids moléculaire: 30 kDa (MW of target protein)

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling