Prohibitin anticorps (C-Term)
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- Antigène Voir toutes Prohibitin (PHB) Anticorps
- Prohibitin (PHB)
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Prohibitin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- Prohibitin antibody was raised against the C terminal of PHB
- Purification
- Affinity purified
- Immunogène
- Prohibitin antibody was raised using the C terminal of PHB corresponding to a region with amino acids AEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLS
- Top Product
- Discover our top product PHB Anticorps primaire
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- Indications d'application
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WB: 1-2 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - Commentaires
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Prohibitin Blocking Peptide, catalog no. 33R-1146, is also available for use as a blocking control in assays to test for specificity of this Prohibitin antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHB antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Antigène
- Prohibitin (PHB)
- Autre désignation
- Prohibitin (PHB Produits)
- Synonymes
- anticorps phb1, anticorps MGC75944, anticorps PHB, anticorps Phb, anticorps ACYPI000080, anticorps phb, anticorps PHB1, anticorps Bap32, anticorps sr:nyz128, anticorps wu:fa18f07, anticorps wu:fb09f05, anticorps prohibitin1, anticorps xphb1, anticorps prohibitin, anticorps prohibitin-2, anticorps prohibitin L homeolog, anticorps PHB, anticorps phb, anticorps LOC484431, anticorps LOC5576054, anticorps Phb, anticorps phb.L
- Sujet
- Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
- Poids moléculaire
- 30 kDa (MW of target protein)
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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