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Prohibitin anticorps (C-Term)

PHB Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN634116
  • Antigène Voir toutes Prohibitin (PHB) Anticorps
    Prohibitin (PHB)
    Épitope
    • 16
    • 13
    • 12
    • 12
    • 9
    • 9
    • 9
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 137
    • 62
    • 60
    • 11
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 116
    • 21
    Lapin
    Clonalité
    • 105
    • 32
    Polyclonal
    Conjugué
    • 70
    • 12
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Prohibitin est non-conjugé
    Application
    • 105
    • 51
    • 46
    • 27
    • 22
    • 22
    • 14
    • 13
    • 11
    • 9
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Prohibitin antibody was raised against the C terminal of PHB
    Purification
    Affinity purified
    Immunogène
    Prohibitin antibody was raised using the C terminal of PHB corresponding to a region with amino acids AEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLS
    Top Product
    Discover our top product PHB Anticorps primaire
  • Indications d'application
    WB: 1-2 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    Prohibitin Blocking Peptide, catalog no. 33R-1146, is also available for use as a blocking control in assays to test for specificity of this Prohibitin antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHB antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène
    Prohibitin (PHB)
    Autre désignation
    Prohibitin (PHB Produits)
    Synonymes
    anticorps phb1, anticorps MGC75944, anticorps PHB, anticorps Phb, anticorps ACYPI000080, anticorps phb, anticorps PHB1, anticorps Bap32, anticorps sr:nyz128, anticorps wu:fa18f07, anticorps wu:fb09f05, anticorps prohibitin1, anticorps xphb1, anticorps prohibitin, anticorps prohibitin-2, anticorps prohibitin L homeolog, anticorps PHB, anticorps phb, anticorps LOC484431, anticorps LOC5576054, anticorps Phb, anticorps phb.L
    Sujet
    Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
    Poids moléculaire
    30 kDa (MW of target protein)
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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