CD80 anticorps (FITC)

N° du produit ABIN642339

Cet anticorps anti-CD80 est un anticorps Rat détectant CD80 dans FACS. Adapté pour Souris.

Aperçu rapide pour CD80 anticorps (FITC) (ABIN642339)

Antigène: CD80

Reactivité: Souris

Hôte: Rat

Conjugué: Cet anticorp CD80 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-CD80 anticorps (FITC)

Specificité: DS-MB-03886 recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.

Attributs du produit: Rat Anti-Mouse CD80, FITC-labeled

Immunogène: BCL1 cells expressing CD80

Isotype: IgG2a

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 0.1 mg/ml

Buffer: Phosphate buffered saline pH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD80

Antigène: CD80

Autre désignation: CD80

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints