HLA-ABC anticorps

N° du produit ABIN642915

Cet anticorps anti-HLA-ABC est un anticorps Rat détectant HLA-ABC dans FACS, IP et IHC (fro). Adapté pour Humain.

Aperçu rapide pour HLA-ABC anticorps (ABIN642915)

Antigène: HLA-ABC

Reactivité: Humain

Hôte: Rat

Conjugué: Cet anticorp HLA-ABC est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-HLA-ABC anticorps

Specificité: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells. DS-MB-01537 recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this antibody binds in the alpha1 domain. Recent studies have shown that this antibody may be able to induce apoptosis in activated but not resting T cells (1).

Attributs du produit: Rat Anti-Human HLA ABC

Purification: Purified

Immunogène: PhA activated human peripheral blood lymphocytes.

Isotype: IgG2b

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur HLA-ABC

Antigène: HLA-ABC

Autre désignation: HLA ABC

Sujet: This antibody does not cross reacts with Fab or F(ab')2 of IgG. Some cross reaction with IgG of other species such as horse and sheep was observed. No cross reaction with human IgA, IgE or IgM.

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints