Clusterin anticorps

N° du produit ABIN644018

L’anticorps anti-Clusterin Polyclonal Lapin est utilisé pour la détection de Clusterin dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Clusterin anticorps (ABIN644018)

Antigène: Clusterin (CLU)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Clusterin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Clusterin anticorps

Fonction: Rabbit Anti-Human CLU / ApoJ

Specificité: DS-PB-00501 recognizes human clusterin (also known as apolipoprotein J). Clusterin is a ubiquitous glycoprotein which exists in at least two distinct isoforms, a proapoptotic nuclear form, of 49kDa, and a prosurvival secretory form with a molecular weight of 75-80kDa. Clusterin is implicated in several diverse physiological processes including sperm maturation, cell differentiation, and apoptosis. Clusterin upregulation has been reported in various human malignancies, including bladder, prostate, and breast tumours. Following specific stress induced injury, secretory clusterin acts as a molecular chaperone, scavenging denatured proteins outside cells. It has been shown to be upregulated in Alzheimer's disease, retinitis pigmentosa, glomerulonephritis, atherosclerosis and myocardial infarction.

Attributs du produit: Cytoskeleton

Purification: Purified

Immunogène: Antisera to Clusterin were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Isotype: IgG

Information d'application

Indications d'application: Immunohistology - Paraffin, Western Blotting

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur Clusterin

Antigène: Clusterin (CLU)

Autre désignation: CLUSTERIN

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling