Caspase 7 anticorps (C-Term)

N° du produit ABIN644997

Cet anticorps anti-Caspase 7 Polyclonal Lapin (ABIN644997) détecte spécifiquement Caspase 7 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Caspase 7 anticorps (C-Term) (ABIN644997)

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Caspase 7 anticorps

Épitope: C-Term

Fonction: Rabbit Anti-Human CASP7 (C-term)

Specificité: DS-PB-00381 recognizes an epitope within the C-terminal region (CT) of Caspase7, a 35kDa cysteine protease, otherwise known as ICE like Apoptotic Protease 3 (ICELAP3). Caspase7, a member of the ICE/Ced3 subfamily, is an executioner caspase which undergoes proteolytic cleavage of its precursor to form active p12 and p20 subunits. Evidence that activation of Caspase7 occurs during cell death induced by the cytokine death receptors Fas/APO1 and the receptor of tumor necrosis factor (TNFR1), coupled with the fact that granzymeB activated Caspase7 cleaves the nuclear enzyme poly (ADPribose) polymerase (PARP), suggests an important role for Caspase7 in both cytokinemediated and GranzymeB mediated apoptosis pathways.

Réactivité croisée: Souris, Rat (Rattus)

Attributs du produit: Phosphorylation/Apoptosis/Signal Transduction/Regulation

Purification: Purified

Immunogène: Antisera to human Caspase-7 (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Isotype: IgG

Information d'application

Indications d'application: Immunohistology - Paraffin, Western Blotting

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur Caspase 7

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Autre désignation: Caspase-7

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity