PYCARD anticorps

N° du produit ABIN645848

Il existe 3+ publications pour ce produit. L’anticorps anti-PYCARD not_set Chèvre est utilisé pour la détection de PYCARD dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour PYCARD anticorps (ABIN645848)

Antigène: PYCARD (PYD and CARD Domain Containing (PYCARD))

Reactivité: Humain

Hôte: Chèvre

Conjugué: Cet anticorp PYCARD est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PYCARD anticorps

Specificité: Peptide ELISA: Antibody detection limit dilution 1:32,000. Western Blot: Approx. 22kDa band observed in Hela and Human Kidney lysates (predicted MW of 22kDa according to NP_037390.2). Recommended for use at 1-3µg/ml.

Réactivité croisée: Humain

Attributs du produit: Goat Anti-ASC / TMS1

Immunogène: Peptide with sequence C-RESQSYLVEDLERS, from the C Terminus of the protein sequence according to NP_037390.2, NP_660183.1, NP_660184.1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-PYCARD (ABIN645848)

Ansari, Dutta, Veettil, Dutta, Iqbal, Kumar, Roy, Chikoti, Singh, Chandran: "Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses." dans: PLoS pathogens, Vol. 11, Issue 7, pp. e1005019, (2015) (PubMed).

Singh, Kerur, Bottero, Dutta, Chakraborty, Ansari, Paudel, Chikoti, Chandran: "Kaposi's sarcoma-associated herpesvirus latency in endothelial and B cells activates gamma interferon-inducible protein 16-mediated inflammasomes." dans: Journal of virology, Vol. 87, Issue 8, pp. 4417-31, (2013) (PubMed).

Ansari, Singh, Dutta, Veettil, Dutta, Chikoti, Lu, Everly, Chandran: "Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells." dans: Journal of virology, Vol. 87, Issue 15, pp. 8606-23, (2013) (PubMed).

Détails sur PYCARD

Antigène: PYCARD (PYD and CARD Domain Containing (PYCARD))

Autre désignation: ASC / TMS1

Sujet: Synonyms: PYCARD, PYD and CARD domain containing, ASC, CARD5, MGC10332, TMS, TMS1, apoptosis-associated speck-like protein containing a CARD, caspase recruitment domain protein 5, target of methylation-induced silencing-1

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome