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Phospholamban anticorps

PLN Reactivité: Humain, Rat, Souris ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7248713
  • Antigène Voir toutes Phospholamban (PLN) Anticorps
    Phospholamban (PLN)
    Reactivité
    • 83
    • 23
    • 22
    • 3
    • 2
    • 2
    • 2
    Humain, Rat, Souris
    Hôte
    • 83
    • 1
    • 1
    Lapin
    Clonalité
    • 83
    • 2
    Polyclonal
    Conjugué
    • 32
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Phospholamban est non-conjugé
    Application
    • 31
    • 26
    • 26
    • 26
    • 12
    • 10
    • 9
    • 8
    • 7
    • 6
    • 6
    • 4
    • 1
    ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogène
    Synthetic peptide of human PLN
    Isotype
    IgG
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    Discover our top product PLN Anticorps primaire
  • Indications d'application
    IHC 1:50-1:100, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.26 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Phospholamban (PLN)
    Autre désignation
    PLN (PLN Produits)
    Synonymes
    anticorps LOC100226261, anticorps plb, anticorps cmd1p, anticorps CMD1P, anticorps CMH18, anticorps PLB, anticorps Plb, anticorps Plm, anticorps phospholamban, anticorps PLN, anticorps pln, anticorps Pln
    Sujet
    The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.
    UniProt
    P26678
    Pathways
    Negative Regulation of Transporter Activity
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