Caspase 3 anticorps (Cleaved-Asp175)

N° du produit ABIN650861

L’anticorps Lapin Polyclonal anti-Caspase 3 a été validé pour IHC (p) et DB. Il convient pour détecter Caspase 3 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour Caspase 3 anticorps (Cleaved-Asp175) (ABIN650861)

Antigène: Caspase 3 (CASP3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Clone: RB25833

Détail du produit anti-Caspase 3 anticorps

Épitope: AA 149-175, Cleaved-Asp175

Homologie: B, M, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Cleaved antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from human Cleaved.

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:50~100. DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Caspase 3 (ABIN650861)

Chen, Liu, Wei, Wu, Luo, Yuan, Luo, Chen: "The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1." dans: Scientific reports, Vol. 6, pp. 32189, (2018) (PubMed).

Luo, Sun, Wei, Luo, Yang, Liu, Guo, Chen: "Functional Characterization of Long Noncoding RNA Lnc_bc060912 in Human Lung Carcinoma Cells." dans: Biochemistry, Vol. 54, Issue 18, pp. 2895-902, (2015) (PubMed).

Détails sur Caspase 3

Antigène: Caspase 3 (CASP3)

Autre désignation: CASP3

Sujet: CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

Poids moléculaire: 31608

ID gène: 836

NCBI Accession: NP_004337, NP_116786

UniProt: P42574

Pathways: Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation