14-3-3 zeta anticorps (AA 65-93)

N° du produit ABIN652428

Cet anticorps anti-14-3-3 zeta est un anticorps Lapin Polyclonal détectant 14-3-3 zeta dans WB, IHC (p) et FACS. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour 14-3-3 zeta anticorps (AA 65-93) (ABIN652428)

Antigène: 14-3-3 zeta (YWHAZ)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 zeta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB22149

Détail du produit anti-14-3-3 zeta anticorps

Épitope: AA 65-93

Homologie: B, C, Rat, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 amino acids from the Central region of human YWHAZ.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-14-3-3 zeta (ABIN652428)

Joshi, Su, Chandramouli, Khoo, Jeong, Young, Lessey, Fazleabas: "Altered expression of microRNA-451 in eutopic endometrium of baboons (Papio anubis) with endometriosis." dans: Human reproduction (Oxford, England), Vol. 30, Issue 12, pp. 2881-91, (2015) (PubMed).

Détails sur 14-3-3 zeta

Antigène: 14-3-3 zeta (YWHAZ)

Autre désignation: YWHAZ

Sujet: YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.

Poids moléculaire: 27745

ID gène: 7534

NCBI Accession: NP_001129171, NP_001129172, NP_001129173, NP_001129174, NP_003397, NP_663723

UniProt: P63104

Pathways: Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location