C5 anticorps (N-Term)

N° du produit ABIN652518

Cet anticorps anti-C5 est un anticorps Lapin Polyclonal détectant C5 dans WB, IHC (p) et FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour C5 anticorps (N-Term) (ABIN652518)

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB21866

Détail du produit anti-C5 anticorps

Épitope: AA 253-281, N-Term

Specificité: This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260~289 amino acids from the N-terminal region of human C5.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 AA from the N-terminal region of human C5.

Isotype: IgG

Information d'application

Indications d'application: WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-C5 (ABIN652518)

Zhang, Huang, Jing, Fu, Yuan, Xia, Cai, Gan, Chen, Zou, Long, Wang, Wang, Xu: "SAK-HV Triggered a Short-period Lipid-lowering Biotherapy Based on the Energy Model of Liver Proliferation via a Novel Pathway." dans: Theranostics, Vol. 7, Issue 6, pp. 1749-1769, (2018) (PubMed).

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: C5

Sujet: C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
Synonyms: Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain, CPAMD4, C5

Poids moléculaire: 188305 DA

ID gène: 727

UniProt: P01031

Pathways: Système du Complément, Carbohydrate Homeostasis