LDLR anticorps (AA 391-419)
Aperçu rapide pour LDLR anticorps (AA 391-419) (ABIN652907)
Antigène
Voir toutes LDLR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 391-419
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Homologie
- X, B, Ha, Pig, Rb, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids of human LDLR.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- LDLR (Low Density Lipoprotein Receptor (LDLR))
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Autre désignation
- LDLR
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Sujet
- The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
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Poids moléculaire
- 95376
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ID gène
- 3949
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NCBI Accession
- NP_000518, NP_001182727, NP_001182728, NP_001182729, NP_001182732
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UniProt
- P01130
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Pathways
- Hepatitis C, Lipid Metabolism
Antigène
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