CYP11B2 anticorps (AA 120-147)

N° du produit ABIN655163

Détail du produit anti-CYP11B2 anticorps

Antigène: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Épitope: AA 120-147

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP11B2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CYP11B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-147 amino acids from the Central region of human CYP11B2.

Clone: RB16930

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur CYP11B2

Antigène: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Autre désignation: CYP11B2 (CYP11B2 Produits)

Synonymes: anticorps ALDOS, anticorps CPN2, anticorps CYP11B, anticorps CYP11BL, anticorps CYPXIB2, anticorps P-450C18, anticorps P450C18, anticorps P450aldo, anticorps Cpn2, anticorps Cyp11b, anticorps Cyp11b-2, anticorps Cp45as, anticorps Cyp11b3, anticorps RNCP45AS, anticorps cytochrome P450 family 11 subfamily B member 2, anticorps cytochrome P450, family 11, subfamily b, polypeptide 2, anticorps aldosterone synthase, anticorps cytochrome P450, family 11, subfamily B, polypeptide 2, anticorps cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2, anticorps CYP11B2, anticorps Cyp11b2

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Poids moléculaire: 57560

ID gène: 1585

NCBI Accession: NP_000489

UniProt: P19099

Pathways: ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour