CYP11B2 anticorps (Middle Region)

N° du produit ABIN2776971

Détail du produit anti-CYP11B2 anticorps

Antigène: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Épitope: Middle Region

Reactivité: Humain, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP11B2 est non-conjugé

Application: Western Blotting (WB)

Séquence: RRLAEAEMLL LLHHVLKHFL VETLTQEDIK MVYSFILRPG TSPLLTFRAI

Homologie: Horse: 79%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CYP11B2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CYP11B2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 503 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CYP11B2 (ABIN2776971)

Doi, Satoh, Maekawa, Nakamura, Fustin, Tainaka, Hotta, Takahashi, Morimoto, Takase, Ito, Sasano, Okamura: "Isoform-specific monoclonal antibodies against 3β-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism." dans: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 2, pp. E257-62, (2014) (PubMed).

Détails sur CYP11B2

Antigène: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Autre désignation: CYP11B2 (CYP11B2 Produits)

Synonymes: anticorps ALDOS, anticorps CPN2, anticorps CYP11B, anticorps CYP11BL, anticorps CYPXIB2, anticorps P-450C18, anticorps P450C18, anticorps P450aldo, anticorps Cpn2, anticorps Cyp11b, anticorps Cyp11b-2, anticorps Cp45as, anticorps Cyp11b3, anticorps RNCP45AS, anticorps cytochrome P450 family 11 subfamily B member 2, anticorps cytochrome P450, family 11, subfamily b, polypeptide 2, anticorps aldosterone synthase, anticorps cytochrome P450, family 11, subfamily B, polypeptide 2, anticorps cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2, anticorps CYP11B2, anticorps Cyp11b2

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein local
Alias Symbols: ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450C18, P450aldo
Protein Interaction Partner: CYP11B2, CYP11B1, CYP11A1, FDX1,
Protein Size: 503

Poids moléculaire: 55 kDa

ID gène: 1585

NCBI Accession: NM_000498, NP_000489

UniProt: P19099

Pathways: ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour