KAT2B anticorps (C-Term)

N° du produit ABIN656013

Cet anticorps anti-KAT2B est un anticorps Lapin Polyclonal détectant KAT2B dans WB. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour KAT2B anticorps (C-Term) (ABIN656013)

Antigène: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT2B est non-conjugé

Application: Western Blotting (WB)

Clone: RB14386

Détail du produit anti-KAT2B anticorps

Épitope: AA 802-832, C-Term

Homologie: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PCAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human PCAF.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-KAT2B (ABIN656013)

Xiong, Svingen, Sarmento, Smyrk, Dave, Khanna, Lomberk, Urrutia, Faubion: "Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene." dans: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 307, Issue 6, pp. R608-20, (2014) (PubMed).

Détails sur KAT2B

Antigène: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Autre désignation: PCAF

Sujet: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Poids moléculaire: 93013

ID gène: 8850

NCBI Accession: NP_003875

UniProt: Q92831

Pathways: Signalisation p53, Regulation of Carbohydrate Metabolic Process