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MED14 anticorps (AA 586-615)

Cet anticorps anti-MED14 est un anticorps Lapin Polyclonal détectant MED14 dans WB et FACS. Adapté pour Humain et Souris.
N° du produit ABIN656136

Aperçu rapide pour MED14 anticorps (AA 586-615) (ABIN656136)

Antigène

Voir toutes MED14 Anticorps
MED14 (Mediator Complex Subunit 14 (MED14))

Reactivité

  • 24
  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 27
  • 3
Lapin

Clonalité

  • 27
  • 3
Polyclonal

Conjugué

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MED14 est non-conjugé

Application

  • 18
  • 14
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

Clone

RB20179
  • Épitope

    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 586-615

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This MED14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from the Central region of human MED14.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. WB: 1:4000. FC: 1:25

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    MED14 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    Date de péremption

    6 months
  • Antigène

    MED14 (Mediator Complex Subunit 14 (MED14))

    Autre désignation

    MED14

    Sujet

    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

    Poids moléculaire

    160607

    ID gène

    9282

    NCBI Accession

    NP_004220

    UniProt

    O60244

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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