Cyclin D3 anticorps

N° du produit ABIN6566666

L’anticorps anti-Cyclin D3 Polyclonal Lapin est utilisé pour la détection de Cyclin D3 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour Cyclin D3 anticorps (ABIN6566666)

Antigène: Cyclin D3 (CCND3)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin D3 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: KO Validated

Détail du produit anti-Cyclin D3 anticorps

Specificité: This antibody ist KO validated.

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CCND3 (NP_001751.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cyclin D3

Antigène: Cyclin D3 (CCND3)

Autre désignation: CCND3

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 36kDa

Calculated_MW: 9kDa/22kDa/24kDa/32kDa

ID gène: 896

UniProt: P30281

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process