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Cyclin D3 anticorps

KO Validated CCND3 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5963256
  • Antigène Voir toutes Cyclin D3 (CCND3) Anticorps
    Cyclin D3 (CCND3)
    Reactivité
    • 108
    • 45
    • 35
    • 16
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 95
    • 15
    Lapin
    Clonalité
    • 87
    • 23
    Polyclonal
    Conjugué
    • 50
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cyclin D3 est non-conjugé
    Application
    • 80
    • 34
    • 28
    • 27
    • 26
    • 19
    • 15
    • 15
    • 10
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This antibody ist KO validated.
    Purification
    Affinity purification
    Classe de qualité
    KO Validated
    Immunogène
    Recombinant fusion protein of human CCND3 (NP_001751.1).
    Isotype
    IgG
    Top Product
    Discover our top product CCND3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Cyclin D3 (CCND3)
    Autre désignation
    CCND3 (CCND3 Produits)
    Synonymes
    anticorps zgc:103502, anticorps CCND3, anticorps 9230106B05Rik, anticorps AA682053, anticorps AL024085, anticorps AW146355, anticorps C78795, anticorps cyclin D3, anticorps ccnd3, anticorps CCND3, anticorps Ccnd3
    Sujet
    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire

    Observed_MW: 36kDa

    Calculated_MW: 9kDa/22kDa/24kDa/32kDa

    ID gène
    896
    UniProt
    P30281
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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