ALDH2 anticorps

N° du produit ABIN6567396

Cet anticorps anti-ALDH2 est un anticorps Lapin Polyclonal détectant ALDH2 dans WB, IHC et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ALDH2 anticorps (ABIN6567396)

Antigène: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDH2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ALDH2 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human ALDH2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALDH2

Antigène: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Autre désignation: ALDH2

Sujet:

Synonyms: Acetaldehyde dehydrogenase 2,Aldehyde dehydrogenase 2 family (mitochondrial),Aldehyde dehydrogenase 2 family,Aldehyde dehydrogenase mitochondrial,Aldehyde dehydrogenase,mitochondrial,ALDH 2,ALDH class 2,ALDH E2,ALDH-E2,Aldh2,ALDH2,ALDHI,ALDM,Liver mitochondrial ALDH,MGC1806,Mitochondrial aldehyde dehydrogenase 2,MS767,Nucleus encoded mitochondrial aldehyde dehydrogenase 2

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: 53kDa

Calculated_MW: 50kDa/56kDa

ID gène: 217

UniProt: P05091