GCN2 anticorps

N° du produit ABIN6567595

Cet anticorps Lapin Polyclonal détecte spécifiquement GCN2 dans WB, IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GCN2 anticorps (ABIN6567595)

Antigène: GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCN2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GCN2 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human EIF2AK4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GCN2

Antigène: GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))

Autre désignation: EIF2AK4

Sujet:

Synonyms: E2AK4,Eif2ak4,Eukaryotic Translation Initiation Factor 2 alpha kinase 4,Eukaryotic translation initiation factor 2-alpha kinase 4,GCN2,GCN2 eIF2alpha kinase,GCN2 like protein,GCN2-like protein,KIAA1338,MGCN2

Background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

Poids moléculaire:

Observed_MW: 187kDa

Calculated_MW: 69kDa/183kDa/186kDa

ID gène: 440275

UniProt: Q9P2K8

Pathways: ER-Nucleus Signaling, Hepatitis C