TAPBP anticorps

N° du produit ABIN6567907

L’anticorps Lapin Polyclonal anti-TAPBP a été validé pour WB, IHC et IF. Il convient pour détecter TAPBP dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TAPBP anticorps (ABIN6567907)

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAPBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TAPBP anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human TAPBP

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TAPBP

Antigène: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Autre désignation: TAPBP

Sujet:

Synonyms: NGS 17,NGS-17,NGS17,TAP associated protein ,TAP binding protein ,TAP binding protein (tapasin),TAP BP,TAP-associated protein,TAP-binding protein,TAPA,Tapasin,TAPBP,TPN,TPSN,TPSN

Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Poids moléculaire:

Observed_MW: 50kDa

Calculated_MW: 38kDa/43kDa/47kDa/53kDa

ID gène: 6892

UniProt: O15533