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MICA anticorps

MICA Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6568196
  • Antigène Voir toutes MICA Anticorps
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Reactivité
    • 70
    • 18
    • 14
    • 11
    • 7
    • 5
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 37
    • 33
    Lapin
    Clonalité
    • 37
    • 34
    Polyclonal
    Conjugué
    • 45
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MICA est non-conjugé
    Application
    • 45
    • 37
    • 33
    • 19
    • 17
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human MICA (NP_000238.1).
    Isotype
    IgG
    Top Product
    Discover our top product MICA Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Autre désignation
    MICA (MICA Produits)
    Synonymes
    anticorps MIC-A, anticorps PERB11.1, anticorps MHC class I polypeptide-related sequence A, anticorps MICA
    Sujet
    This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
    Poids moléculaire

    Observed_MW: 43kDa

    Calculated_MW: 31kDa/42kDa

    ID gène
    100507436
    UniProt
    Q29983
    Pathways
    Activation of Innate immune Response, Transition Metal Ion Homeostasis
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