ABCB7 anticorps

N° du produit ABIN6568439

Cet anticorps Lapin Polyclonal détecte spécifiquement ABCB7 dans IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ABCB7 anticorps (ABIN6568439)

Antigène: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCB7 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ABCB7 anticorps

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ABCB7 (NP_004290.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ABCB7

Antigène: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Autre désignation: ABCB7

Sujet: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire:

Observed_MW: 83kDa

Calculated_MW: 78kDa/82kDa

ID gène: 22

UniProt: O75027

Pathways: Transition Metal Ion Homeostasis