RNASEH2A anticorps

N° du produit ABIN6568584

Détail du produit anti-RNASEH2A anticorps

Antigène: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNASEH2A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human RNASEH2A (NP_006388.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RNASEH2A

Antigène: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Autre désignation: RNASEH2A (RNASEH2A Produits)

Synonymes: anticorps 2400006P09Rik, anticorps RNASEHI, anticorps RNHIA, anticorps RNHL, anticorps zgc:56307, anticorps AGS4, anticorps JUNB, anticorps ribonuclease H2 subunit A, anticorps ribonuclease H2, large subunit, anticorps ribonuclease H2, subunit A, anticorps ribonuclease H2 subunit A L homeolog, anticorps rnaseh2a, anticorps RNASEH2A, anticorps Rnaseh2a, anticorps rnaseh2a.L

Sujet: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.

Poids moléculaire:

Observed_MW: 33kDa

Calculated_MW: 33kDa

ID gène: 10535

UniProt: O75792