NAE1 anticorps (AA 172-200)
Aperçu rapide pour NAE1 anticorps (AA 172-200) (ABIN656991)
Antigène
Voir toutes NAE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 172-200
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Homologie
- Pr, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This NAE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the Central region of human NAE1.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. IHC-P: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- NAE1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Date de péremption
- 6 months
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- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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Autre désignation
- NAE1
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Sujet
- The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 60246
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ID gène
- 8883
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NCBI Accession
- NP_001018169, NP_001018170, NP_003896
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UniProt
- Q13564
Antigène
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