SART1 anticorps

N° du produit ABIN6571846

Cet anticorps anti-SART1 est un anticorps Lapin Polyclonal détectant SART1 dans WB et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SART1 anticorps (ABIN6571846)

Antigène: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SART1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-SART1 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human SART1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IP 1:20 - 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SART1

Antigène: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Autre désignation: SART1

Sujet:

Synonyms: Ara 1,ARA1,HOMS 1,HOMS1,hSART 1,hSART1,hSnu 66,hSnu66,IgE autoantigen,MGC2038,SART 1,SART1 259,SART1(259) protein,SART1(800) protein,SART1259,Snu 66,Snu66 ,Squamous cell carcinoma antigen recognised by T cells,Squamous cell carcinoma antigen recognized by T cells 1,U4/U6.U5 tri snRNP associated 110 kDa protein ,U4/U6.U5 tri snRNP associated protein 1

Background: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

Poids moléculaire:

Observed_MW: 120kDa

Calculated_MW: 90kDa

ID gène: 9092

UniProt: O43290

Pathways: Ribonucleoprotein Complex Subunit Organization