CD33 anticorps (AA 88-117)
Aperçu rapide pour CD33 anticorps (AA 88-117) (ABIN657464)
Antigène
Voir toutes CD33 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 88-117
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This CD33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human CD33.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- CD33 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Date de péremption
- 6 months
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- CD33
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Autre désignation
- CD33
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Sujet
- Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
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Poids moléculaire
- 39825
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ID gène
- 945
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NCBI Accession
- NP_001076087, NP_001171079, NP_001763
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UniProt
- P20138
Antigène
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