MDM4-binding Protein anticorps (AA 128-157)

N° du produit ABIN657782

L’anticorps anti-MDM4-binding Protein Polyclonal Lapin est utilisé pour la détection de MDM4-binding Protein dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MDM4-binding Protein anticorps (AA 128-157) (ABIN657782)

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDM4-binding Protein est non-conjugé

Application: Western Blotting (WB)

Clone: RB33903

Détail du produit anti-MDM4-binding Protein anticorps

Épitope: AA 128-157

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MDM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human MDM4.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: MDM4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur MDM4-binding Protein

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Autre désignation: MDM4

Sujet: The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene.

Poids moléculaire: 54864

ID gène: 4194

NCBI Accession: NP_001191100, NP_001191101, NP_001265445, NP_001265446, NP_001265447, NP_001265448, NP_002384

UniProt: O15151

Pathways: Cycle Cellulaire