MDM4-binding Protein anticorps (pSer367)

N° du produit ABIN7138576

Détail du produit anti-MDM4-binding Protein anticorps

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Épitope: pSer367

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDM4-binding Protein est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 367 (T-I-S(p)-A-P) derived from Human MDM4.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MDM4-binding Protein

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Autre désignation: MDM4 (MDM4 Produits)

Synonymes: anticorps mdmx, anticorps HDMX, anticorps MDMX, anticorps MRP1, anticorps wu:fa09h09, anticorps wu:fi33d10, anticorps 4933417N07Rik, anticorps AA414968, anticorps AL023055, anticorps AU018793, anticorps AU021806, anticorps C85810, anticorps Mdmx, anticorps MDM4, p53 regulator S homeolog, anticorps MDM4, p53 regulator, anticorps transformed mouse 3T3 cell double minute 4, anticorps mdm4.S, anticorps MDM4, anticorps Mdm4, anticorps mdm4

Sujet:

Background: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Aliases: DKFZp781B1423 antibody, Double minute 4 antibody, Double minute 4 human homolog of p53 binding protein antibody, Double minute 4 protein antibody, HDMX antibody, MDM 4 antibody, Mdm2 like p53 binding protein antibody, Mdm2-like p53-binding protein antibody, MDM4 antibody, Mdm4 p53 binding protein homolog mouse antibody, Mdm4 protein antibody, MDM4 related protein 1 antibody, Mdm4 transformed 3T3 cell double minute 4 antibody, Mdm4 transformed 3T3 cell double minute 4 p53 binding protein antibody, Mdm4 transformed 3T3 cell double minute 4 p53 binding protein mouse antibody, MDM4_HUMAN antibody, Mdmx protein antibody, MGC132766 antibody, Mouse double minute 4 homolog antibody, Mouse double minute 4 human homolog of p53 binding protein antibody, MRP 1 antibody, MRP1 antibody, p53 binding protein antibody, p53 BINDING PROTEIN MDM4 antibody, p53-binding protein Mdm4 antibody, Protein Mdm4 antibody, Protein Mdmx antibody

UniProt: O15151

Pathways: Cycle Cellulaire