ABL1 anticorps (AA 613-641)
Aperçu rapide pour ABL1 anticorps (AA 613-641) (ABIN657828)
Antigène
Voir toutes ABL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 613-641
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This Mouse Abl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the Central region of mouse Abl1.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. IHC-P: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Mouse Abl1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Date de péremption
- 6 months
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- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
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Autre désignation
- Abl1
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Sujet
- Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
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Poids moléculaire
- 122673
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ID gène
- 11350
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NCBI Accession
- NP_001106174, NP_033724
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UniProt
- P00520
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Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
Antigène
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