Neuregulin 2 anticorps (AA 361-410)

N° du produit ABIN6579377

Cet anticorps anti-Neuregulin 2 Polyclonal Lapin (ABIN6579377) détecte spécifiquement Neuregulin 2 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Neuregulin 2 anticorps (AA 361-410) (ABIN6579377)

Antigène: Neuregulin 2 (NRG2)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuregulin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Neuregulin 2 anticorps

Épitope: AA 361-410

Fonction: Neuregulin-2 Antibody

Specificité: Neuregulin-2 Polyclonal Antibody detects endogenous levels of Neuregulin-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human NRG2. AA range:361-410

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Neuregulin 2

Antigène: Neuregulin 2 (NRG2)

Autre désignation: NRG2

Sujet:

Synonyms: NRG2, NTAK, Pro-neuregulin-2, membrane-bound isoform, Pro-NRG2

Background: This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010],

Gene Name: NRG2

Protein Name: Pro-neuregulin-2 membrane-bound isoform

Poids moléculaire: 91 kDa

ID gène: 9542

UniProt: O14511

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway