Dual Specificity Phosphatase 3 (DUSP3) (AA 136-185) anticorps

N° du produit ABIN6579411

L’anticorps anti-Dual Specificity Phosphatase 3 Polyclonal Lapin est utilisé pour la détection de Dual Specificity Phosphatase 3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour Dual Specificity Phosphatase 3 (DUSP3) (AA 136-185) anticorps (ABIN6579411)

Antigène: Dual Specificity Phosphatase 3 (DUSP3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit

Épitope: AA 136-185

Fonction: VHR Antibody

Specificité: VHR Polyclonal Antibody detects endogenous levels of VHR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the C-terminal region of human DUSP3. AA range:136-185

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détail du antigène

Antigène: Dual Specificity Phosphatase 3 (DUSP3)

Autre désignation: DUSP3

Sujet:

Synonyms: DUSP3, VHR, Dual specificity protein phosphatase 3, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase, VHR

Background: The protein encoded byThis gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast ca

Gene Name: DUSP3

Protein Name: Dual specificity protein phosphatase 3

Poids moléculaire: 20 kDa

ID gène: 1845

UniProt: P51452

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades