ITGA2 anticorps (AA 1081-1130)
Aperçu rapide pour ITGA2 anticorps (AA 1081-1130) (ABIN6579455)
Antigène
Voir toutes ITGA2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1081-1130
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Fonction
- Integrin α2 Antibody
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Specificité
- Integrin α2 Polyclonal Antibody detects endogenous levels of Integrin α2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human ITGA2. AA range:1081-1130
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- ITGA2 (Integrin alpha 2 (ITGA2))
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Autre désignation
- ITGA2
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Sujet
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Synonyms: ITGA2, CD49B, Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b
Background: integrin subunit alpha 2(ITGA2) Homo sapiens This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
Gene Name: ITGA2
Protein Name: Integrin alpha-2
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Poids moléculaire
- '130 kDa
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ID gène
- 3673
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OMIM
- 176760
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UniProt
- P17301
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Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
Antigène
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