Retinoblastoma Binding Protein 8 anticorps (C-Term)

N° du produit ABIN657950

L’anticorps anti-Retinoblastoma Binding Protein 8 Polyclonal Lapin est utilisé pour la détection de Retinoblastoma Binding Protein 8 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Retinoblastoma Binding Protein 8 anticorps (C-Term) (ABIN657950)

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé

Application: Western Blotting (WB)

Clone: RB34059

Détail du produit anti-Retinoblastoma Binding Protein 8 anticorps

Épitope: AA 763-792, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RBBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 763-792 amino acids from the C-terminal region of human RBBP8.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: RBBP8 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur Retinoblastoma Binding Protein 8

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Autre désignation: RBBP8

Sujet: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

Poids moléculaire: 101942

ID gène: 5932

NCBI Accession: NP_002885, NP_976036, NP_976037

UniProt: Q99708

Pathways: Cycle Cellulaire, Réparation de l'ADN