Betacellulin anticorps (AA 32-111)

N° du produit ABIN6654020

Cet anticorps anti-Betacellulin est un anticorps Lapin Polyclonal détectant Betacellulin dans WB, IHC (p) et ELISA (Capture). Adapté pour Humain.

Aperçu rapide pour Betacellulin anticorps (AA 32-111) (ABIN6654020)

Antigène: Betacellulin (BTC)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Betacellulin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)

Détail du produit anti-Betacellulin anticorps

Épitope: AA 32-111

Purification: Antigen affinity purified

Immunogène: Amino acids D32-Y111 from the human protein were used as the immunogen for the BTC antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the BTC antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture): 1-5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the BTC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Betacellulin

Antigène: Betacellulin (BTC)

Autre désignation: BTC / Betacellulin

Sujet: Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

UniProt: P35070

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway