CASR anticorps (AA 926-1078)

N° du produit ABIN6654119

Cet anticorps anti-CASR est un anticorps Souris Monoclonal détectant CASR dans WB et FACS. Adapté pour Humain.

Aperçu rapide pour CASR anticorps (AA 926-1078) (ABIN6654119)

Antigène: CASR (Calcium-Sensing Receptor (CASR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CASR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 11E9-

Détail du produit anti-CASR anticorps

Épitope: AA 926-1078

Purification: Protein G affinity

Immunogène: Human CASR recombinant protein (amino acids Q926-S1078) was used as the immunogen for the CASR antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the CASR antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL (human),Flow Cytometry: 1-3 μg/1x10^6 cells (mouse)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CASR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CASR

Antigène: CASR (Calcium-Sensing Receptor (CASR))

Autre désignation: Calcium Sensing Receptor / CASR

Sujet: The calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.

UniProt: P41180

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis